Pheochromocytoma is a rare, non-cancerous (benign) tumour that occurs in the central point of the adrenal gland. Every person has two adrenal organs, one over each kidney. Customarily, pheochromocytoma is known as the "10% tumour". It is a neuroendocrine tumour of the medulla of the adrenal glands beginning in the chromaffin cells, which secretes extreme measures of catecholamines, epinephrine and norepinephrine. In the case of pheochromocytoma, the adrenal glands discharge hormones that cause persistent or episodic high blood pressure. If left untreated, pheochromocytoma can become hazardous to other body parts. It particularly affects the cardiovascular system.
A vast majority of people suffering from a pheochromocytoma are between 20 to 50 years of age. The younger generation is vulnerable to it as well. A carefully monitored treatment to remove pheochromocytoma often returns blood pressure to normal.
The adrenal glands are two little endocrine glands that lie over the kidneys. They secrete and circulate vital hormones and steroids for the body’s normal functioning. Adrenaline and cortisol are the two hormones which are crucial for us.
· Immune system’s functionality
The abnormal functioning may happen spontaneously or might be activated by the factors mentioned below:
Food items high in tyramine, a substance that influences blood pressure, additionally can trigger an abnormal functioning as well. These nourishments include:
Certain drugs that can trigger asymptomatic abnormality are:
● Monoamine oxidase inhibitors (MAOIs, for example, phenelzine (Nardil), tranylcypromine (Parnate) and isocarboxazid (Marplan)
When to see a Doctor?
Diverse conditions can cause the signs and indications of pheochromocytoma. It's essential to get a prompt diagnosis if any abnormal symptoms are observed.
Although hypertension is an essential indication of a pheochromocytoma, many people with hypertension don't have an adrenal tumour. It’s advised to consult your doctor if any of the accompanying components apply to you:
● A family history of a related hereditary issue: endocrine neoplasia, type II (MEN II); von Hippel-Lindau disease; familial paraganglioma or neurofibromatosis 1 (NF1)
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